High-Throughput Screening

We offer a vertically-integrated discovery platform for expedient and reliable efficacy and toxicology testing. Our state-of-the-art high throughput screening facility can be customized for screening purposes to establish the potency ratings for our natural product libraries or customer-provided libraries. Factors we screen for include cell, receptor, enzyme based assays, antimicrobial, antifungal, antioxidant, and anti-inflammatory activities to name a few.

  • Solutions that address the problems of, and perform, high-throughtput Screening assays.
  • Use of multiple cell lines.
  • Intensive parallel approach.
  • Collapsed timeline and quicker lead decisions.
  • Comprehensive picture of a coumpound's mode of action.


PPI offers several solutions to address the problems and perform high-throughput screening assays. The company uses multiple cell line offerings that allow one to run a panel of counter screen assays for a desired target and incorporate studies of toxic receptors, as it is an inducible and titratable system. At PPI we are trying out an intensive parallel approach, where we apply a lot of resources upfront including assay development, screening more focused libraries. Our screening, assay development, and chemistry groups work hand in hand during this process. The hope is to collapse the timeline and enable quicker lead decisions. An additional goal is to interpret compound effects from multiple assays that use diverse technologies to gain a comprehensive picture of a compound's mode-of-action.